IMI Site Sat, 18 Sep 2021 14:19:56 +0000 en-US hourly 1 IMI Site 32 32 Spectrum Pharmaceuticals Presents Late-Breaking Oral Presentation of Poziotinib Data in First-Line NSCLC Patients with Exon 20 HER2 Insertion Mutations at ESMO 2021 Sat, 18 Sep 2021 12:45:00 +0000

Initial data from cohort 4 of the ongoing ZENITH20 clinical trial show 44% ORR in 48 first-line patients treated with 16 mg poziotinib once daily

HENDERSON, Nevada, September 18, 2021– (BUSINESS WIRE) – Spectrum Pharmaceuticals, Inc. (NasdaqGS: SPPI), a biopharmaceutical company specializing in innovative and targeted oncology therapies, today announced the presentation of the safety and efficacy results of the cohort 4 of the ZENITH20 clinical trial. These data are from 48 first-line non-small cell lung cancer (NSCLC) patients with HER2 exon insertion mutations who received 16 mg of poziotinib orally once daily. These results showed a confirmed objective response rate (ORR) of 44%, as assessed centrally by an independent image review committee using the RECIST 1.1 criteria. The data was presented late at the 2021 congress of the European Society of Medical Oncology (ESMO) to be held in Paris from September 16 to 20, 2021.

“The data presented in Paris for Cohort 4 are very encouraging,” said François Lebel, MD, medical director of Spectrum Pharmaceuticals. “There is currently no specific approved treatment for patients with NSCLC with exon 20 HER2 insertion mutations. These data represent an important step in our development of poziotinib for patients with significant medical need. “

A copy of the ESMO presentation titled “Efficacy and Safety of Poziotinib in Naïve Treatment of NSCLC harboring HER2 exon 20 mutations: A multinational Phase 2 study (ZENITH20-4)” presented by Dr Robin Cornelissen, Erasmus MC Cancer Institute in Rotterdam, is available on the Spectrum corporate website at

ZENITH20 Trial Design and Early Safety and Efficacy Data for Cohort 4

Cohort 4 of the ZENITH20 clinical trial is recruiting treatment-naïve NSCLC patients with exon 20 HER2 insertion mutations. This cohort is studying the efficacy of poziotinib with a QD and BID dosing strategy (in progress). Poziotinib 16 mg was administered orally once daily to the first 48 patients resulting in dose reductions / interruptions due to toxicity. The primary endpoint was ORR centrally assessed by an independent image review board using RECIST 1.1 criteria. Secondary endpoints included disease control rate (DCR), duration of response (DoR), progression-free survival (PFS), and safety.

The primary endpoint of ORR was 44% (95% CI: 29.5-58.8%) in the 48 patients treated, including complete response. 88% of patients (42/48) experienced tumor reduction with a DCR of 75%. The median DoR was 5.4 months (range 2.8-19.1+). The median PFS was 5.6 months (range 0 to 20.2+). 88% of patients had dose interruptions and 77% had reductions from the initial dose of 16 mg once daily, while 13% had interruptions related to adverse events (AEs). The most common treatment-related Grade ≥ 3 adverse reactions were rash (35%), stomatitis (20%), diarrhea (14%) and paronychia (8%). In addition, only 1 patient had Grade ≥ 3 pneumonitis. Poziotinib demonstrated clinically significant anti-tumor activity in patients with newly diagnosed NSCLC with exon 20 HER2 mutations at a dose of 16 mg a times a day. The safety profile was manageable and similar to that previously observed in previous studies and other second generation tyrosine kinase inhibitors. The 8 mg BID portion of Cohort 4 continues to actively recruit.

About the ZENITH20 clinical trial

The ZENITH20 study includes seven cohorts of patients with NSCLC. Cohorts 1 (EGFR) and 2 (HER2) in NSCLS patients previously treated with exon 20 mutations and Cohort 3 (EGFR) in first-line patients have completed recruitment. Cohort 4 (HER2) in patients with first-line NSCLC with exon 20 mutations is still recruiting patients. Cohorts 1 to 4 are each fed independently for a predefined statistical hypothesis and the primary endpoint is the objective response rate (ORR). Cohort 5 comprises previously treated or treatment naïve NSCLC patients with EGFR or HER2 exon insertion mutations. Cohort 6 includes NSCLC patients with classic EGFR mutations who progressed during treatment with first-line osimertinib and developed an additional EGFR mutation. Cohort 7 includes patients with NSCLC with a variety of less common mutations in EGFR or HER2 exons 18-21 or extracellular or transmembrane domains.

On Spectrum Pharmaceuticals, Inc.

Spectrum Pharmaceuticals is a biopharmaceutical company focused on the acquisition, development and commercialization of new and targeted oncology therapies. Spectrum has a strong track record of successfully executing the biopharmaceutical business model, from licensing and acquisition of differentiated drugs, to clinical development of new assets, to successful regulatory approvals and commercialization. in a competitive healthcare market. Spectrum has an advanced pipeline with new assets that meet unmet needs. This pipeline has the potential to transform the business in the near future. For more information on Spectrum Pharmaceuticals, please visit

Forward-looking statement – This press release may contain forward-looking statements concerning future events and the future performance of Spectrum Pharmaceuticals that involve risks and uncertainties that could cause actual results to differ materially. These statements are based on the beliefs and current expectations of management. These statements include, but are not limited to, statements relating to Spectrum’s business and its future, including certain important business milestones, the timing and results of FDA decisions, and any statements relating to the Spectrum’s intention, belief, plans or expectations or its management, or which are not a statement of historical fact. Risks that could cause actual results to differ include, but are not limited to, the possibility that the different methodologies, assumptions and applications used by the Company to assess particular parameters of safety or efficacy may produce statistical results. different, and although the company believes the data collected from clinical trials of its product candidates, including poziotinib, is positive, that data may not be sufficient to warrant FDA approval; the possibility that the success of the first clinical trials, especially if they are based on a small sample of patients, will not lead to the success of the subsequent clinical trials, and other unforeseen events during the clinical trials which could lead to delays or other undesirable consequences; other uncertainties inherent in the development of new products; the possibility that Spectrum’s new and existing drug candidates, including poziotinib, may not ultimately prove to be safe or effective; the possibility that our existing and new drug candidates, if approved, may not be more effective, safer or more cost effective than competing drugs; the possibility that our efforts to acquire or license and develop other drug candidates will fail; our reliance on third parties for clinical trials, manufacturing, distribution and quality control; and other risks which are more fully described in the Company’s reports filed with the Securities and Exchange Commission (SEC). The company does not intend to update these forward-looking statements and expressly disclaims any obligation to update the information contained in this press release, except as required by law. For more information about the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as the risks associated with Spectrum’s business in general, see the risk information in the annual report on Spectrum’s Form 10-K for the fiscal year ended December 31, 2020, and in subsequent reports on Forms 10-Q and 8-K and other documents filed with the SEC by Spectrum.

SPECTRUM PHARMACEUTICALS, INC.® is a registered trademark of Spectrum Pharmaceuticals, Inc and its subsidiary. REDEFINING CANCER CARE ™ and the Spectrum Pharmaceuticals logos are trademarks owned by Spectrum Pharmaceuticals, Inc. All other trademarks are the property of their respective owners.

© 2021 Spectrum Pharmaceuticals, Inc. All rights reserved

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Robert uhl
Managing Director, Westwicke ICR

Kurt gustafson
Financial director

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On file: County of Trumbull | News, Sports, Jobs Sat, 18 Sep 2021 06:17:48 +0000

WHAT: County Commissioners Meeting Wednesday

WHO: Mauro Cantalamessa, Niki Frenchko and Frank Fuda


• Authorized the purchase by the Engineer’s Office of a used Coronado Freightliner for $ 49,000;

• Authorization granted to the engineer to close Wakefield Creek road between national road 11 and Ridge road until today for the replacement of a culvert;

• Passed a resolution to proceed with the construction of the K contract of the Blueprint Waterline Initiative project for the sanitary sewer district and the public water system of the Township of Braceville in Southington, and to announce sealed bids for the construction of the project;

• Accepted Substantial Completion Certification for the Swift Drive Sanitary Sewer Improvement Project in Vienna;

• Approval of a change order with Rudzik Excavating Inc. of Struthers for the Swift Drive project, adding $ 64,824 to the project and bringing the total to $ 755,478. The contract was for $ 80,554 as of the 2019 estimate, and the change order, caused by the cost of repairing concrete and asphalt driveways in a private easement where the sanitary sewer is located, will be paid with grant and loan funds;

• Approval of changes to the regulations of the Workforce Development Council;

• Awarded bids for youth employment services to Youthbuild-TMHA of Warren for $ 276,001 and Jobs For Ohio Graduates (JOG) of Akron for $ 376,915 after a request for proposals. Both were the only offers submitted;

• Appointed Paula Vivoda-Klotz as Clerk of the Council of Commissioners at a rate of $ 29.40 per hour in a 2-1 vote, with Frenchko “no” vote;

• Named Lisa DeNunzio Blair as Deputy Clerk of the Council of Commissioners at $ 23.06 an hour in a 2-1 vote, with Frenchko “no” vote;

• Approved the hiring of John Hickey as Director of the Trumbull County Emergency Management Agency at $ 65,000 per year;

• Agreements granted to Mirkin and Associates of Youngstown and Garwin Inc. of Hubbard to provide on-demand transportation services to the general public, persons with disabilities and persons under the age of 60, until the allocated $ 49,999 in contractual funds are exhausted;

• Allowed the advertising of sealed proposals to provide on-demand transportation services to people with disabilities and those 60 years of age or older as of November 1 and lasting approximately 12 months. There is $ 1.160 million available using Seniors Levy funds, federal funds, and Trumbull County Developmental Disorders Board funds;

• Documents approved to pay $ 110,554 for HVAC upgrades at the Job and Family Services building, 280 N. Park Ave., and the county jail for $ 65,470, awarding contracts to Comfort Systems USA of Hamilton after a request for proposals;

• Sending a letter of support to the US Department of Commerce for the Eastgate Regional Council of Governments and its “Rebuilding a better regional challenge” proposal;

• Awarded a $ 28,200 proposal to A and N Restaurant Equipment and Supplies of Warren for a blast chiller / freezer and electrical upgrades for the installation of Trumbull mobile meals on East Market Street;

• Fuda and Cantalamessa did not support several of Frenchko’s motions to withdraw his proposals from the September 9 meeting;

• Awarded a contract to Integrated Voting Systems of Berea to provide printed voting pages to the Trumbull County Electoral Council for four elections through the 2023 primary, with a maximum cost per election of $ 50,400, for a total of $ 201,600, rejecting an offer from Midwest Direct of Cleveland;

• Approval of the $ 32,100 contract between the Compagnies Lamar de Girard and Job and Family Services for 60 outdoor postings;

• Discussed how to manage the distributions of US bailout funds. Final guidelines are still needed before any decisions are made on how to use the funds. Commissioners plan to hold public meetings to hear ideas on the use of funds, what type of ranking tool should be used to assess proposed uses of funds, and whether a committee or consultant should help plan how to use the funds. funds.

– Renée Fox

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Animals late to shelters due to veterinarian shortage – NBC Los Angeles Fri, 17 Sep 2021 22:45:17 +0000

If you’ve recently tried to get your pet to a vet, you know it can take weeks to get an appointment due to the nationwide shortage of vets.

Part of the reason for this shortage is that a high number of people adopted animals during the pandemic, but it is also in part because vets and veterinary technicians have a high rate of burnout.

Many vets earn less than half of the amount paid by doctors, despite the high cost of training.

“The liability is extremely high when you go out as a licensed veterinarian,” said Ashlee Sprague, vice chair of the board of directors of Priceless Pets. “The work is extremely hard, the hours are long, the pay is not incredible.”

The shortage of vets leads to overcrowding in shelters, as animals cannot be adopted until they are spayed or neutered.

“You envision it taking around six to eight weeks for a regular checkup for your personal veterinarian, let alone a shelter animal,” said Shelley Fonglesong, vice chair of the board of directors at Upland Animal Shelter.

At Priceless Pets in Chino Hills, the only full-time vet is struggling to keep up with demand.

“It’s very frustrating,” Sprague said. “We are already a low cost clinic, so we are a lot of people’s last resort before returning pets to the shelter for medical problems.”

Some pet owners who are unable to find cheap veterinary services resort to abandoning their animals.

“So they will either choose the cheaper alternative which is unfortunately euthanasia, or turn it into a shelter,” Sprague said. “They will let him go like a stray animal … Unfortunately, this only increases the amount of admission to shelters and more and more pets are being euthanized. This is a big deal.”

She added that pet owners can help by keeping their pets healthy with diet and exercise, and not clogging veterinary clinics with minor issues.

“Don’t come in to cut nails or clean ears, things that can be taken care of elsewhere,” Sprague said.

If you don’t mind waiting a few weeks for a shelter animal to be spayed or neutered, you can help ease the burden at shelters by embracing NBCLA and Telemundo’s Clear the Shelters campaign, until September 19 . And if you can’t adopt, consider donating to your local shelter.

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Vertex Pharmaceuticals (VRTX) wins as the market goes down: what you need to know Fri, 17 Sep 2021 21:45:21 +0000

Vertex Pharmaceuticals (VRTX) closed at $ 188.30 on the last trading session, marking a rise of 0.64% from the previous day. This move exceeded the 0.91% daily loss of the S&P 500.

Prior to today’s trading, the drugmaker’s shares had lost 4.07% in the past month. This delayed the 0.52% loss of the medical sector and the 0.01% gain of the S&P 500 during this period.

Wall Street will research VRTX for positivity as the date of its next earnings report approaches. The company is expected to post EPS of $ 3.08, up 16.67% from the previous year quarter. Meanwhile, Zacks’ consensus estimate for revenue projects net sales of $ 1.84 billion, up 19.31% from the previous year.

For the full year, our Zacks consensus estimates project earnings of $ 12.37 per share and revenue of $ 7.25 billion, which would represent changes of + 19.86% and + 16.81%, respectively, over the previous year.

Investors should also note any recent changes in analyst estimates for VRTX. These revisions help show the ever-changing nature of short-term business trends. As a result, we can interpret positive estimate revisions as a good sign for the company’s business outlook.

Based on our research, we believe that these estimate revisions are directly related to stock movements close to the team. Investors can take advantage of this by using the Zacks Ranking. This model takes into account these changes in estimate and provides a simple and workable scoring system.

The Zacks Rank system, which ranges from # 1 (strong buy) to # 5 (strong sell), has an impressive externally audited outperformance history, with # 1 stocks generating an average annual return of + 25% since 1988. Zacks Consensus EPS estimate has remained stagnant over the past month. VRTX is currently a Zacks Rank # 2 (Buy).

Looking at its valuation, VRTX holds a forward P / E ratio of 15.13. This valuation marks a discount compared to the average Forward P / E for its sector of 26.75.

Investors should also note that VRTX currently has a PEG ratio of 1.54. This metric is used similarly to the famous P / E ratio, but the PEG ratio also takes into account the expected growth rate of the stock’s earnings. Medical – Biomedical and genetic stocks have, on average, a PEG ratio of 1.54 based on yesterday’s closing prices.

The Medical – Biomedical and Genetic industry is part of the Medical sector. This group has a Zacks Industry Rank of 195, which places it in the lowest 24% of all 250+ industries.

The Zacks Industry Rank includes is ranked from best to worst in terms of the average Zacks Rank of individual companies in each of these industries. Our research shows that the top 50% of industries top the bottom half by a factor of 2 to 1.

You can find more information on all of these metrics, and more, at

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Each was selected by a Zacks expert as the # 1 favorite stock to earn + 100% or more in 2021. Previous recommendations climbed + 143.0%, + 175.9%, + 498.3% and + 673.0%.

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Vertex Pharmaceuticals Incorporated (VRTX): Free Stock Analysis Report

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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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Lauren Book tables bill requiring schools to provide free access to sanitary products Fri, 17 Sep 2021 18:55:39 +0000 The bill would require tampons and sanitary napkins in all public schools from kindergarten to grade 12.

A state senator wants to give girls and women in Florida public schools free access to tampons and sanitary napkins.

Senator Lauren’s Book on Friday tabled the law on learning with dignity (SB 248,) which would apply to all public schools, K-12. If adopted and enacted, it would enter into force on July 1, 2022.

The book bill follows the California Assembly’s passage of the “Menstrual Fairness for All Act of 2021” last week. The measure, Assembly Bill 367, recognizes that access to menstrual products is “a basic human right and is vital to ensuring the health, dignity and full participation of all Californians in public life.” “

The Scottish Parliament passed a new law last year declaring access to menstrual products a human right and requiring all designated public places to provide menstrual products free of charge to anyone who needs them.

The Book Bill is not worded as broadly as either of these pieces of legislation.

SB 248 notes that menstrual hygiene products cannot be “easily given up or replaced” and that when students have access to “quality menstrual hygiene products, they are able to continue their daily lives with good health. minimum interruption ”.

At the time of going to press, no complementary bills have been tabled in the House.

There have been several in recent years showing that girls and women may have difficulty purchasing menstrual products and that lack of access can compromise their learning.

A 2019 study by researchers at the College of Public Health and Social Justice at Saint Louis University found that nearly two-thirds of women surveyed couldn’t afford period-related products and that 46% of women they could not afford both food and menstrual hygiene. some products. Additionally, the study found that 21% of women surveyed lack supplies on a monthly basis.

Due to lack of access, some girls miss school because of their period. The World Bank found in 2005 that if a girl misses four days of school each month because of her period, she will miss between 10% and 20% of her college career.

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SWOT, Feasibility and Yield Analysis for a New Project in 2021 – Stillwater Current Fri, 17 Sep 2021 08:23:58 +0000

Global Pet Veterinary Products Industry Production, Sales and Consumption Status and Outlook 2021 Professional Market Research Report

The Veterinary Pet Products market research report presents the most recent changes in the market in a statistical format including the market size, growth, and overall forecast for the current period. The research also sheds light on the newest key players in the Veterinary Pet Products market, which are further classified on the basis of their market footprint and product offerings. In addition, a section of the report focuses on the current strategies implemented by the actors in their respective regions. Additionally, the Veterinary Pet Products market research examines the driving forces, opportunities, and challenges that the Pet Veterinary Products industry will face during the forecast period.

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The competitive landscape of the market research includes a broader analysis of the regions of the world which are expected to capture the essence of the market in its broadest category. The Veterinary Pet Products market study also encompasses the market in terms of the most recent outlook and emerging market scenarios, based on in-depth knowledge and valuable information gleaned from industry experts on the Veterinary Companion Animal Market during the early stages of research. Additionally, the Veterinary Pet Products market report contains some factors such as business opportunities, latest market innovations, upcoming trends, growth analysis, and latest key players that can provide the consumer a detailed market estimate. Our team of researchers and analysts have put a lot of effort into creating the Veterinary Pet Products market study by providing important and reliable consumables for every fact that has been presented.

Some of the major players in the Global Pet Veterinary Products Market are: Zoetis, Dechra Veterinary Products, Merck Animal Health, Meiji, Vetoquinol, Boehringer Ingelheim, Ouro Fino Saude, Elanco Animal Health, Bayer Animal Health, Virbac, Ceva , Animalcare Group, Parnell

The detailed information provided in the Veterinary Pet Products market research study with the help of key players presented in the study will help our readers to understand the strategies implemented with the help of the methodology followed and guidelines observed. for the collection and use of the data collected.

When performing secondary and primary research, market revenue and production volumes are prioritized. Other factors such as customer needs / preferences, research findings, estimated market size, and data sources are taken into account when completing the final study of the report. The Veterinary Pet Products market research study provides a comprehensive assessment for the forecast period.

The Global Pet Veterinary Products Market analyzes and discusses the impact of COVID-19 on the market. The global catastrophe has caused untold damage to all sectors of the pet veterinary market. However, as the world approaches a pre-pandemic situation, the Pet Veterinary Products market is expected to be driven by rapid industrialization, increasing demand for Pet Veterinary Products, and stringent government conditions and regulations to maintain itself. comply with industry standards. The Veterinary Pet Products market study examines all aspects of the Veterinary Pet Products industry from various angles including various drivers, restraints, challenges, and opportunities during the forecast period. Further, the Veterinary Pet Products study divides the market into key players, Veterinary Pet Products types, and application and use cases.

Important product types on the market: Medicines, Vaccine

Benefits taken by the end user: Dogs, Cats

The report concludes with a competitive landscape of the Veterinary Pet Products market, comprising a detailed dashboard of major players, their respective market share, key strategies implemented, and their most recent mergers and acquisitions for the period. forecast. A SWOT analysis segment is also included in the market strategies. We use a variety of primary and secondary research methodologies that differ in their research methods to categorize our collected data.

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Global Women’s Wet Wipes and Wipes Market 2021 with Pre-Post COVID-19 Impact Analysis by Product (Common Type, Sanitary Type, Antiseptic Type); By application (cleaning women, common use) Fri, 17 Sep 2021 07:44:29 +0000

Global Womens Wet Wipes and Wipes Market Overview, Regional Analysis, Market Share and Competitive Analysis

The Global Womens Wet Wipes And Wipes Market report comprehensively elaborates on current trends, drivers and restraints aimed at providing a comprehensive overview of the Womens Wet Wipes and Wipes industry. The report also presents the risks and emphasizes the solutions that can be used to overcome the prevailing concerns with an unwavering methodology. The Women’s Wet Wipes and Wipes market report covers the historical 5 years of data along with a decade of forecast built using information gathered from proprietary sources, primary and secondary research methodologies and ‘an internal model for analysis and verification of facts. . Some of the major players operating in the global Women’s Wet Wipes and Wipes Market include Hengan Group, P&G, Clorox, Diamond Wipes International, Johnson & Johnson, Nice-Pak Products, GS Coverting, Tongling Jieya, SC Johnson, Kimberly-Clark, Albaad Massuot, Cascades, Beiersdorf, Suominen Corporation, Georgia-Pacific, Pigeon, SCA , Oji Holdings,.

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COVID-19 impact analysis:

In this report, the pre- and post-COVID impact on market growth and development is well described for a better understanding of the Women’s Wet Wipes And Wipes Market on the basis of financial and industrial analysis. The COVID-19 pandemic has affected a number of markets and the global Women’s Wet Wipes and Wipes Market is no exception. However, the dominant players in the global Women’s Wet Wipes and Wipes market are determined to adopt new strategies and seek new financing resources to overcome the growing obstacles to the market growth.

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Why invest in the report?

• Detailed study on the dynamic segmentation of the Women’s Wet Wipes and Wipes market.
• Comprehensive survey of the Global Women’s Wet Wipes and Wipes Market
• Universal review of important market adaptations and developments
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• Holistic review of market strategies adapted by key players
• Study of the size and volume of the market based on historical, present and foreseeable growth projections
• In-depth analysis of the existing competition at regional and global levels which will have a huge influence on future business expansion.

This report segments the market based on the following types:

Common type, Sanitary type, Antiseptic type

On the basis of Application, the market is segmented into:

Women’s cleaning, common use

The competitive landscape of the market research includes a broader analysis on the regions comprising the United States, Canada and Mexico in North America, Peru, Brazil, Argentina and the rest of North America. South under South America, Germany, Italy, UK, France, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Hungary, Lithuania, Austria, Ireland , Norway, Poland, Rest of Europe in Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Vietnam, Rest of Asia-Pacific (APAC) in Asia- Pacific (APAC), South Africa, Saudi Arabia, UAE, Kuwait, Israel, Egypt, Rest of Middle East & Africa (MEA) which are expected to capture the essence of the market in its broadest category.

Our analysts predict health growth in terms of CAGR and product value over the forecast period with the change in outlook of the general population. In addition, the study also enumerates the driving forces and barriers that stand between complete autonomy and current production techniques and values. The global distribution of women’s wet wipes and wipes varies from region to region; however, our analyst determined the distribution based on market share. The main regions to which the Women’s Wet Wipes and Wipes industry adheres are noted below:

• North America (United States, Canada and Mexico)
• Europe (Germany, France, United Kingdom, Russia and Italy)
• Asia-Pacific (Japan, China and Southeast Asia)

For an additional revised list of market players in 2020, request a sample report:

The Wet Wipes and Wipes for Women Market report answers the following question:

• What is the expected growth rate of the market during the forecast period?
• Which regional market is assumed to have the lion’s share?
• What are the expected factors driving the Women’s Wet Wipes and Wipes market forward?
• What are the opportunities likely to trigger industrial growth in the years to come?
• What are the challenges and threats that will have huge impact on the growth of the Wet Wipes and Wipes for Women market?
• Who are the key players in the market?
• What are the major trends that will impact the growth of the market?

Reasons for Buying the Wet Wipes and Wipes for Women Market Research:

• The development of business strategies is discussed taking into account the continuing trends driving the global Women’s Wet Wipes and Wipes industry.
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• Organized sales and marketing efforts are identified taking into account the strategies employed by major players in the Women’s Wet Wipes and Wipes market.
• Verified financial reports from proprietary sources are provided to make identical decisions for greater increase in business value.

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DeSantis wants to buy monoclonal antibodies directly from pharmaceutical companies Thu, 16 Sep 2021 22:38:13 +0000

Tallahassee, Florida – The governor of Florida is not happy that the Biden administration is taking over the distribution of monoclonal antibodies.

Gov. Ron DeSantis said Thursday he was concerned the state didn’t have enough.

“There will be a lot of confusion and the patient will suffer,” he said. said De Santis. “We will work like hell to overcome the hurdles the HHS and Biden administrations place on us.”

DeSantis is making monoclonal antibodies an important factor in the fight against the latest outbreaks of COVID-19. If given early enough, the chances of a sick person going to the hospital are reduced by 75%.

However, due to limited supply, health and wellness services Said earlier this week Made changes that prevent hospitals and treatment facilities from directly ordering early treatment for COVID-19.

Instead, HHS returned to its pre-vaccination position. The officials analyze the need there and send the cargo to the state for division.

“The HHS determines how much product each state and territory receives each week,” said Kirsten Allen, HHS national press secretary for COVID Response. In the statement. “State and regional health services then identify the sites that receive the products and their quantities. This system makes it possible to maintain a geographically and temporally equitable distribution across the country, and the states and territories. We will provide the state with a constant and fair supply over the next few weeks.

DeSantis called the deal change crude and pledged to work directly with drug company GlaxoSmithKline to evade federal authorities by purchasing the monoclonal drug Sotrovimab.

“The federal government bought all of the Regenerons,” DeSantis said. “With that in mind, you can’t buy directly from Regeneron. I think you can order Sotrobimab. If you can, do it.

The Governor has opened 25 monoclonal sites in Sunshine. According to his office, Florida needs about 72,000 doses per week to meet demand. this week’s allowance Less than half, about 31,000.

Florida is one of the seven states that make up the majority of recent monoclonal orders.

The White House champions change. Florida is one of seven states that account for 70% of recent monoclonal orders, so officials said it would ensure fairness in all states.

Press Officer Jen Psaki manipulate Monoclonal concerns during his regular briefing.

“Our offer is not unlimited and we believe it should be fair,” she said. “Our role as the government overseeing the whole country is to be fair about how we distribute. We’re not going to give Florida a bigger proportion than Oklahoma. “

Beyond that, critics have also said DeSantis needs to stop treating monoclonal drugs as frontline protection.

Some lawmakers and state doctors continue to urge the governor to focus more on virus mitigation and vaccines. They also prevent hospitalization and are plentiful across the country.

DeSantis wants to buy monoclonal antibodies directly from pharmaceutical companies

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A day in the life of a pathologist toxicologist veterinarian Thu, 16 Sep 2021 22:06:35 +0000 In this episode of The Vet Blast podcast, Monique Y. Wells, VMD, MS, shares what inspired her to pursue a veterinary toxicological pathology, what her career entails, and more.

Monique Y. Wells, VMD, MS, was determined to become a veterinarian from a young age, but when she began her journey at the University of Pennsylvania School of Veterinary Medicine, doubts about this pursuit began to emerge. to surface. However, when she persevered into her sophomore year, she immediately fell in love with the niche field known as pathology.

In this episode of The Vet Blast podcast, Wells shared with Adam Christman, DVM, MBA, what ignited his passion, as well as the inner workings of the toxicology pathologist profession.

“[What resonated with me in pathology] got to the bottom of it, so exploring the ‘final answer’ as to what made an animal sick or dead, but also … what I knew about pathology at the time doing biopsies and autopsies and things like this. Just the visual aspect of it was so compelling to me, ”Wells said.

Wells then touched on the toxicological aspect of her career and how she focuses on understanding harmful chemicals.

“Toxicology in industry is all about the development of chemicals … and all of those things that have the potential to cause harm, the toxicological pathologist looks at these entities – these chemicals – and sees how many of them are needed to cause damage, how they cause damage, and whether those harmful things can be reversed after a certain period of time.

Listen below to learn more about Well’s fascinating career and find out how she has used it as a platform to help propel veterinary medicine in developing countries.

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Biden faces new Texas border emergency Thu, 16 Sep 2021 18:24:29 +0000

SAN ANTONIO – The Biden administration faces a new humanitarian emergency along the border in South Texas, where thousands of migrants, mostly Haitians, waiting to be placed in border patrol custody sleep outside under a road bridge after crossing the Rio Grande en masse.

Authorities in Del Rio, Texas say more than 8,000 migrants have arrived at the impromptu camp, many in the past 36 hours, and they expect thousands more in the coming days. Images from the bridge site show dense crowds, including families and young children, and deteriorating sanitary conditions.

The migrants appear to be part of a larger wave of Haitian migrants, many of whom arrived in Brazil and other South American countries after the 2010 earthquake and are on their way again, embarking on a grueling and dangerous journey to reach the United States. More than 29,000 Haitians have arrived in the past 11 months, according to the latest customs and border protection figures, including some from mixed families whose children were born in Brazil, Chile or other countries of the world. ‘South America.

They roamed the jungles of Darien Gap in Panama, navigated migrant camps and criminal gangs in Central America, and dodged border guards and troops along highways in southern Mexico.

We don’t know how many more can happen. CBP is working to send additional officers to Del Rio to help process migrants, assigning them numbers as they line up to be formally apprehended, the first step in an asylum claim or another form of American protection.

“The Border Patrol is increasing its numbers in the Del Rio area and coordinating efforts within DHS and other relevant federal, state and local partners to immediately address the current level of encounters with migrants and to facilitate a safe process,” humane and orderly, ”CBP said. in a report. “To avoid injury from heat-related illnesses, the shaded area under the Del Rio International Bridge serves as a temporary staging site while migrants wait to be placed in USBP custody. “

US agents say some migrants are fording the river to Mexico to buy meals and supplies, and street vendors from Mexico have also moved to sell food inside the camp.

CBP said it was providing clean water, towels and other supplies to the site, but an agent from the Del Rio area said sanitary conditions were deteriorating. There are 20 portable toilets at the site, according to Jon Anfinsen, the top union official for border patrols in the Del Rio area.

“We’re trying to bring all the resources we can, but it’s a logistical nightmare,” he said. “We are bringing in officers from across the country to help, but they won’t be here today, and we’re just trying to keep our heads above water.”

Families with young children are given priority, Anfinsen said, to move them out of the bridge area as soon as possible.

“Many agents are mothers and fathers, and seeing children in this situation is sad for everyone,” he said. “Morale is horrible. “

The Biden administration said it would continue to use its emergency authorities under Title 42 of the US Public Health Code to quickly return or “deport” migrants. But Mexican authorities have refused to take back the Haitians in recent months.

The Biden administration reduced deportation flights to Haiti after the assassination of President Jovenel Moïse in July and a magnitude 7.2 earthquake on August 14 that left more than 2,000 dead. And the Department of Homeland Security has extended Protected Temporary Status, or TPS, to the eligibility of Haitians, a measure that allows Haitians living in the United States without legal status to qualify for temporary residence and avoid it. expulsion.

The Del Rio border area has been among the busiest for illegal crossings in recent months as thousands of Haitians, Cubans, Venezuelans and Hondurans descend limestone cliffs on the Mexican side to cross the Rio Grande.

The river is only ankle deep right now at popular crossings, Anfinsen said.

The Democratic Mayor of Del Rio, Bruno “Ralphy” Lozano, said the group has grown steadily in size to more than 8,200 people. “I thought the worst case scenario was having a few people, maybe 150 people roaming the streets,” said Lozano, who warned the Biden administration in a February video that his community needed more. federal support to deal with an increase in level crossings.

“Although I foreshadowed the worst case scenario, it is probably a worst case scenario,” he said. “I need the administration to recognize that there is a real-time border crisis right now and that it is having dire consequences for safety, health and safety.”

In recent months, the city has been a testing ground for Governor Greg Abbott’s more aggressive border security plans, including charging migrants with state crimes such as trespassing.

Val Verde County, which includes Del Rio, chose President Donald Trump in 2020, voting for a top Republican for the first time in decades.

Lozano said that while he initially praised the Republican governor’s efforts, the local justice system was now overwhelmed.

Val Verde County has received funding from the state and hundreds of Texas state troops in recent months to assist border patrol officers. At one point this summer, then sector chief Austin Skero had just four officers patrolling more than 40 miles of river, with officials tied up to process more than 1,000 migrants a day.

Haitian, Venezuelan and Cuban migrants often say they prefer to cross the Del Rio region because of its reputation as comparatively safer than the Rio Grande valley downstream.

Human rights activists have long predicted that unrest in the Mexican border towns of Piedras Negras and Ciudad Acuña would lead to mass migration. Although the route is attractive to migrants who can pay a little more, these communities lack the aid infrastructure and local government support that exist elsewhere in Mexican cities.

Many migrants have arrived at the border in buses that appear to be part of a large smuggling operation, Lozano said. “It looks like there is an off-grid bus system that is not registered with the Mexican government and that drives these people north,” he said.

Some Del Rio residents, especially those living along the river and on ranches, have sounded the alarm in recent months about large groups of migrants appearing on their properties.

The mayor said his city and the migrants are both victims, bearing the brunt of federal political decisions that ignore realities on the ground in border communities.

“You have a favela that has been established overnight with poor people,” Lozano said. “The border patrol is doing their best to deal with these people, but the Del Rio area is 240 miles wide. If the focus here is on those 8,000 people, it opens up a big question: Who is watching the rest of the industry?

Miroff reported from Washington.

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